Application deadline: 31 Dec 2026
Institute: University of Manitoba
Country: Canada
More information: https://umanitoba.ca/medicine/faculty-staff/tanveer-sharif
Are you interested in becoming part of a highly motivated and enthusiastic team of researchers focused on identifying novel treatment strategies for highly aggressive adult and childhood brain tumors?
The Sharif lab, located on the Bannatyne Campus at the University of Manitoba in the heart of Winnipeg, Canada, is home to a cutting-edge research program that investigates novel metabolism-based precision medicine therapies for treating the most common types of malignant brain cancers in children and adults, medulloblastoma (MB) and glioblastoma (GBM).
Read some of our latest research for free in:
• Nature Communications - Metabolism-based targeting of MYC via MPC-SOD2 axis-mediated oxidation promotes cellular differentiation in group 3 medulloblastoma. PMID: 37130865.
• Neuro-Oncology – Disease stage-specific role of the mitochondrial pyruvate carrier suppresses differentiation in temozolomide and radiation-treated glioblastoma. PMID: 39798085.
• Cell Death & Disease – Targeting SRC enhances differentiation and promotes multifaceted cell death mechanisms in recurrent group 3 medulloblastoma. PMID: 42031710. AND Glioblastoma cells that evade chemoradiotherapy-induced cell death exhibit a bifurcated glycolytic program. PMID: 41881949.
Team members will have access and gain training to use state-of-the-art and gold standard research tools and techniques such as our in-house GeoMx Digital Spatial Profiler and Nanostring nCounter platform, dedicated hypoxia tissue culture and imaging suite, and in vivo pre-clinical brain tumor transplantation mouse models.
We have exciting opportunities available for graduate students interested in pursuing a Ph.D. or Master’s degree with the possibility of transferring into a Ph.D. program. Students will receive competitive stipends with opportunities to advance based on performance. Students will have unparalleled opportunities to earn authorship on scientific publications in leading research journals.
Candidates for graduate student positions should be completing their undergraduate degree in a relevant program (e.g., Biology, Biochemistry, Genetics, Microbiology, Pathology, etc.) with a minimum GPA of 3.5. Preference will be given to students graduating with a degree from a Canadian University.
We are seeking candidates who are dedicated, goal-oriented, and innovative to join our dynamic team. Students with background knowledge in cancer biology and prior research experience (e.g., undergraduate research studentships and co-op work terms) are preferred. Strong scientific writing skills and presentation skills are considered an asset.
Interested applicants should send a curriculum vitae and transcripts to tanveer.sharif@umanitoba.ca. Candidates short-listed will be contacted for in-person or virtual interviews.
