On the day guide & Abstracts

Welcome to the EACR-Boehringer Ingelheim Conference: Drugging and Regulating the MAP Kinase Pathway! This page brings together all the information you’ll need while attending this 2025 EACR Virtual Conference. 

Quick Links

• Scientific programme
• Virtual poster discussion sessions
  • Session 1 posters
  • Session 2 posters
• Digital abstracts and posters (Login required for access)
• Participant list (You will receive the password at the start of the conference)
• Code of conduct
• Social media: Post about the conference on social media including LinkedIn, Facebook, and tag us @helloeacr on Instagram and Bluesky.

Zoom

EACR Virtual Conferences run across two Zoom formats – Webinars (for the conference talks) and Meetings (for poster discussion sessions). As an attendee during the webinar sections of the conference, you won’t be able to switch on your camera and you will need to have your microphone enabled by an organiser to ask questions. During the poster discussion sessions, you will be in control of your own camera and microphone. You will need to have both switched on to get the most out of these sessions. 

Accessing the Zoom Webinar links

Approximately 24 hours before the start of each day of the conference, you should receive an email from Zoom with your link to access the conference webinar. As this is an automated email, it might be sorted into your junk folder. If you have not received your email by the morning of the conference, please email Christopher.Iliffe@eacr.org. This webinar link is specific to you and should not be shared with anyone else.

If you click on the link before the conference is due to start, you will see a holding screen. Once the EACR has started the webinar, the system will automatically move you into the conference space. If you need to leave the conference, you can re-join later using the same link.

Asking questions

There are two ways that you can ask questions to our speakers during the conference talks.

If you want to ask your question live, then please use the ‘Raise Hand’ button. This might be located at the top or bottom of your screen. The Chair will invite you to ask your question, and the EACR team will enable your microphone.

If you do not want to ask your question live, then use the Q&A box. This might be found at the bottom of your screen. You will have the option to ask your question anonymously if that is your preference. The Chair will then read questions from the Q&A box on your behalf.

Certificate of attendance

After the conference you will receive an email with a link to a short survey. Please give us your feedback so that we can make improvements for future conferences. After you have completed the survey, you will be able to download and print a Certificate of Attendance.

Virtual poster discussion sessions

Tuesday 11 February 2025 | 16:35-17:35 CET
Wednesday 12 February 2025 | 12:30-13:30 CET

The poster discussion sessions are scheduled to take place at the end of day 1 and the beginning of day 2 of the conference. They will each be held as a separate Zoom meeting. You will receive the links to join these meetings in the email sent to you a week before the conference. During the virtual poster discussion sessions, each poster presenter will have their very own breakout room where they will be displaying their poster. All attendees will have full control over their camera and microphone, be able to communicate using the chat, and navigate across the breakout rooms to view each poster and talk to the poster presenter.

When you first enter the meeting, you will go straight to the 'Lobby'. EACR staff will be there throughout the session should you have any questions. Details of each of the posters on display in the session and their relevant breakout rooms will be shown on the screen in this main area. You can also access the list of posters via our digital abstract book (login required) and further down on this page!

Conference participants are invited to join any of the rooms to browse the posters, discuss the work on show, and make new connections. To navigate to a specific breakout room, click on the ‘Breakout Room’ button and then on the specific room you would like to join. Zoom will then move you to that breakout room. Keep in mind that each poster discussion session only lasts 1 hour, so make sure you leave yourself plenty of time to browse!
 
If you are a poster presenter, you will have your own designated breakout room, which corresponds to your poster number. This space is entirely yours and can be used to present your research however you think is best! We recommend sharing your poster as PowerPoint slides or a presentation. 

Feedback from our previous virtual poster discussion sessions:

"The poster sessions were extremely well-organised and interactive. This type of session provides a very inspiring platform to interact with other people working in the field more openly and facilitates great scientific exchange."

"I felt fully involved in the conference most especially during the breakout session where I was able to present my work and also get to discuss it with other great minds."

"The virtual social and networking experiences provided me with valuable connections and insights that I wouldn’t have been able to gain otherwise."

Poster discussion session 1: Tuesday 11 February 2025
16:35 – 17:35 CET

Posters on display:

Poster 01 - Ana María Fernández-Rodríguez ‘Targeting tumor resistance to Raf1 deletion in NSCLC’

Poster 02 - Paolo Armando Gagliardi ‘Targeting Emergent Properties of Signaling Dynamics: Collective ERK-Activity Waves in PIK3CA H1047R Mutant Cells’

Poster 03 – Rósula García Navas ‘Synergistic antileukemic activity of SOS1 Inhibitor BI-3406 and Imatinib decreases the population of leukemic stem cells and overcomes resistance in Chronic Myeloid Leukemia’

Poster 04 – Giulio Abagnale ‘BRAFV600E iPSCs display cell type dependent sensitivity to MAPK pathway inhibitors during myelopoiesis in a Langerhans Cell Histiocytosis model’

Poster 05 – Marianna Aprile ‘Exploring a novel transdifferentiation strategy in anaplastic thyroid carcinoma for improving therapeutic outcomes’

Poster 06 – Shruti Bhardiya ‘Targeting DUSP6 to combat therapy resistance in HER2-positive breast cancer’

Poster 07 – Soumyajit Biswas ‘Anti-metastatic activity of two novel  sunitinib hydrazone-based metal complexes in non-small cell  lung carcinoma (A549) as TELOMERASE AND POLY (ADP-RIBOSE) POLYMERASE INHIBITOR’

Poster 08 – Maristella Canovai ‘Targeting of the mutated NRAS reduces metabolic activity and cell cycle progression in Multiple myeloma’

Poster 09 – Simona Cataldi ‘COMETT lncRNA as new potential therapeutic target in BRAFV600E-mutated papillary and anaplastic thyroid carcinomas’

Poster 10 – Alen Cebzan ‘Computer-aided drug design of novel MAPK inhibitors utilizing 3D-QSAR modeling and a fragment-based approach, combined with molecular docking and molecular dynamics simulations’

Poster 11 – Aristophane Chay ‘Evaluation of RAF inhibitor response in BRAF non-V600, NRAS, and NF1 mutant melanomas’

Poster 12 – Laura de la Puente ‘ARAF’s surprising lack of impact in NSCLC: a boost for RAF1-targeted therapies’

Poster 13 – Micol E. Fiori ‘Mechanisms and role of PI3K pathway inhibition in colorectal cancer’

Poster 14 – Fabrizio Fontana ‘Dissecting the role of extracellular vesicles in the horizontal transfer of melanoma invasive traits’

Poster 18 – Romi Gupta ‘ASAH1 promotes TNBC growth via the MAP kinase pathway and represents a potential therapeutic target’

This session will end at 17:35 CET so please make sure you give yourself enough time to browse each of the posters on display!

Poster discussion session 2: Wednesday 12 February 2025
12:30 – 13:30 CET

Before the main programme of scientific talks on day 2 we will hold our second 60-minute virtual poster discussion session, showcasing even more posters submitted for the conference. Please make sure you have received the link to this meeting and that you have joined the session by 12:30 CET.

Posters on display:

Poster 15 – Andrea García Pérez ‘Early Overactivation of Non-Muscle Myosin II Contributes to Adaptation to Combined BRAF and MEK Inhibitors in Cutaneous Melanoma’

Poster 16 – Michela Garofalo ‘Identification of survivin as a circulating marker of response to KRAS and Receptor Tyrosine Kinases (RTK) inhibition’

Poster 17 - Sarah Grosche ‘DUSP4 knockdown in BRAF V600E mutant colorectal cancer leads to tumor stasis and MAPK pathway elevation in-vivo’

Poster 19 – Lucía Lomba ‘Development of nanobodies targeting KRAS-RAF1 interaction’

Poster 20 – Luis Luna Ramírez ‘Synergistic therapeutic effects of SOS1 and SHP2 inhibition in aggressive neuroblastoma’

Poster 21 – Ana Moreira ‘Targeting mutated KRAS with PMC79, a new ruthenium drug for pancreatic cancer’

Poster 22 – Caterina Perfetto ‘Synergistic effects of B-raf inhibitors and diclofenac on the glycolytic phenotype and tumor plasticity of BRAF-mutated anaplastic thyroid carcinomas’

Poster 23 – Bernhard Robl ‘Targeting the MAPK-pathway in neurofibromatosis type 1’

Poster 24 – Robyn Schenk ‘SOS1 inhibition in combination with RTK inhibition in models of RTK-amplified cancer’

Poster 25 - Thomas Sevrin ‘Combination of conformation-specific RAF inhibitors synergise to inhibit ERK signalling in pancreatic ductal adenocarcinoma cell lines’

Poster 26 – Pian Sun ‘Elimination of Hyaluronic acid in Pancreatic Ductal Adenocarcinoma (PDAC) as a potential Therapeutic Strategy’

Poster 27 – Mike van Heumen ‘Crosstalk between oncogenic signaling pathways as driver of therapy resistance against small molecule inhibitors in Glioblastoma’

Poster 28 – Marianna Vitiello ‘Targeting oncogenic mutated NRAS in tumor cells using an allele-specific CRISPR approach’

This session will end at 13:30 CET so please make sure you give yourself enough time to browse each of the posters on display!

There will then be a 30-minute break before we move over to Zoom Webinar for our second day of scientific talks.