
Virtual Event : 2 - 3 December 2025
To download and print the programme, use the links below.
Listed times are in Central European Time (CET)
WELCOME TO DAY ONE
Chair: Cédric Blanpain
Mark Dawson Peter MacCallum Cancer Centre, Australia
'Genetic and non-genetic mechanisms of clonal dominance and therapeutic resistance in cancer'
Q&A 13:25-13:35
Direna Alonso-Curbelo IRB Barcelona, Spain
'Epigenetic plasticity at the crossroads of inflammation and pancreatic tumorigenesis'
Q&A 13:55-14:05
Christopher Hanley University of Southampton, UK
Proffered Paper 1: 'TP53 Inactivation and Microenvironmental Cues Coordinate Lineage Plasticity and Therapy Resistance in Lung Adenocarcinoma'
Q&A 14:15-14:20
FLASH TALKS 1
A selection of high-scoring abstracts presented as 3 minute flash talks.
REFRESHMENT BREAK
Chair: Dana Pe'er
Raphael Rodriguez Institut Curie, France
'Chemical control of cell adaptation'
Q&A 15:10-15:20
Sven Größl German Cancer Research Center, Germany
Proffered Paper 2: 'Acidosis orchestrates adaptations of energy metabolism in tumors'
Q&A 15:30-15:35
Marco Fantuz Veneto Institute of Molecular Medicine, Italy
Proffered Paper 3: 'Multi-omic single nuclei profiling of murine pancreas at homeostasis'
Q&A 15:45-15:50
REFRESHMENT BREAK
Adrienne A. Boire Memorial Sloan Kettering Cancer Centre, USA
'Metabolic Reprogramming of Metastases in the Central Nervous System'
Q&A: 16:25-16:35
FLASH TALKS 2
A selection of high-scoring abstracts presented as 3 minute flash talks.
SUMMARY AND CLOSE
Listed times are in Central European Time (CET)
WELCOME TO DAY TWO
Chair: Eduard Batlle
Ilaria Malanchi Francis Crick Institute, UK
'Emergency granulopoiesis and cancer progression'
Q&A 13:25-13:35
Cassandra Burdziak Memorial Sloan Kettering Cancer Centre, USA
'The environment-plasticity axis in tumor progression'
Q&A 13:55-14:05
Tancredi Massimo Pentimalli Max Delbruck Center, Germany
Proffered Paper 4: 'Spatiotemporal dynamics of tumor microenvironment remodeling'
Q&A 14:15-14:20
FLASH TALKS 3
A selection of high-scoring abstracts presented as 3 minute flash talks.
REFRESHMENT BREAK
Chair: Chris Marine
Julie Pannequin Institut de Génomique Fonctionnelle (IGF), France
Proffered Paper 5: 'Impact of 5-Fluorouracil (5-FU) on tumor plasticity'
Q&A 15:00-15:05
The EMBO Keynote Lecture
Eduard Batlle IRB Barcelona, Spain
'Plasticity, therapy resistance and immune evasion in metastatic colorectal cancer'
Q&A 15:25-15:35
Lars Custers ETH Zürich, Switzerland
Proffered Paper 6: 'Malignant differentiation dynamics drive chemotherapeutic escape in colorectal cancer'
Q&A: 15:45-15:50
REFRESHMENT BREAK
Frederic de Sauvage Genentech, USA
'Tumor cell plasticity in colon cancer'
Q&A 16:25-16:35
FLASH TALKS 4
A selection of high-scoring abstracts presented as 3 minute flash talks.
DISCUSSION SESSION
Chris Marine, Cedric Blanpain, Dana Pe'er, Eduard Batlle
'Examining the importance of phenotypic plasticity as a driver of cancer evolution'
SUMMARY AND CLOSE
Abstract submission deadline:
06 October 2025
Registration and Payment deadline:
03 November 2025
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