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Vita-Salute San Raffaele University are recruiting a post-doctoral fellow to work on an AIRC Start-Up funded project which entails extensive collaborations with national and international research Laboratories at the IRCCS Ospedale San Raffaele (OSR) in Milan, Italy.
The project combines innovative approaches including multiplexed genome editing in genetically-engineered mouse models (PMID: 33707235) and single cell sequencing studies to understand the molecular underpinnings of genomic mediators of drug sensitivity and resistance in lung cancer. They will integrate and correlate in vivo results with clinical data, generate patient-derived models (cell lines, organoids, and xenografts), and leverage these unique systems to identify specific genotype-specific cancer vulnerabilities.
The ideal candidate would be an early-career researcher with a creative mind, genuine interests, passionate about science and willing to learn about lung cancer biology and investigate novel therapeutic strategies for patients affected by this disease. They recently obtained a PhD degree in Cellular and Molecular Biology, Medical Oncology, or related disciplines. High motivation, independent working capacity, excellent organizational skills and team spirit are expected and required. They should have a solid background in cancer cell biology, molecular signaling, cell culture and standard molecular biology techniques. Hands-on experience with in vivo models and computational skills would be a plus.
The successful candidate will be offered a 1-year contract with possible extension thereafter and a competitive salary based on proved experience.
Should you need any additional information regarding the project, do not hesitate to email Giorgia Foggetti. Interested candidates will need to send a detailed CV, a cover letter, and contacts for at least 2 references to foggetti.giorgia@hsr.it.