Job and Study Opportunities

Scientific Officer 2 - Liquid Biopsy Research

Other job position

Application deadline: 21 Aug 2022

Institute: Cancer Research UK Manchester Institute
Country: United Kingdom
More information: https://www.cruk.manchester.ac.uk/recruitment/candidate/searchvacancies

• Salary in the range of £20,404 - £26,806 per annum (dependent upon experience)
• Job Ref: MI/22/56
• Duration: fixed term until 31st March 2025 (in first instance)

About the role:
A key aim for the Cancer Biomarker Centre (CBC) is to improve survival for cancer patients through liquid biopsy biomarker research. An exciting opportunity has arisen for a Scientific Officer 2 to join the Nucleic Acid Biomarker (NAB) Team in CBC, within the Cancer Research UK Manchester Institute. The NAB Team has an international reputation and strong track record of high impact publications and development of leading-edge clinical trials using liquid biopsies (Chemi et al. Nat Med. 2019 Oct;25(10):1534-1539, Rothwell et al. Nat Med. 2019 May;25(5):738-743). This post will involve molecular analysis of liquid biopsies, including circulating free DNA and RNA (cfDNA and cfRNA), tumour DNA and RNA and circulating tumour cells (CTCs) using a variety of enrichment, labelling and analysis systems. Techniques developed will include established methodologies incorporating Next Generation Sequencing (NGS), methylation profiling and gene expression analysis as well as the verification and application of novel approaches developed by the NAB team. All the required training and supervision will be provided by working alongside experienced staff.

About you:
You will have a degree in a relevant scientific discipline e.g. biology, biochemistry or medical sciences (or equivalent relevant experience) along with relevant experience working in a cancer and/or molecular biology research setting. Experience and understanding of a range of molecular biology techniques including NGS and PCR is highly desirable, though on work training will be provided. Experience in processing and analysis of clinical samples is desirable. You should be motivated, organised and willing to work as part of a large multidisciplinary team, with a strong desire to learn new skills and advance cancer research. Effective communication, and basic computer skills are essential.

Why choose Cancer Research UK Manchester Institute?
The Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), an Institute of The University of Manchester (www.manchester.ac.uk), is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world. We are currently situated at the internationally-renowned life sciences campus at Alderley Park in Cheshire England, 15 miles from Manchester, a vibrant and dynamic city surrounded by beautiful countryside.

We are partnered with The Christie NHS Foundation Trust in South Manchester (www.christie.nhs.uk), one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.

How to apply?
To apply for this position please visit our website: https://www.cruk.manchester.ac.uk/recruitment/candidate/searchvacancies

For any informal enquiries about this post, please contact Dr Dominic Rothwell: dominic.rothwell@cruk.manchester.ac.uk .