Listed times are in Central European Time (CET)

WELCOME TO DAY ONE

Opening words: Marcus Goncalves

Session 1: Tumour and Host Metabolism

Session Chair: Marcus Goncalves

Ayelet Erez Weizmann Institute of Science, Rehovot, Israel

'Deciphering the metabolic complexity of tumor-host interactions to improve diagnosis and therapy'

Q&A 13:25-13:35

Dimitrios Anastasiou The Francis Crick Institute, London, UK

'Roles of host metabolism in liver cancer'

Q&A 13:55-14:05

Lorenza Bodo Molecular Biotechnology Center "Guido Tarone", Torino, Italy

Proffered Paper 1: 'Impaired cAMP/CREB1 signaling drives mitochondrial dysfunction in skeletal muscle during cancer cachexia'

Q&A 14:15-14:20

FLASH TALKS - Session 1

5 abstracts presented as 3-minute flash talks

REFRESHMENT BREAK

Session 2: Cachexia and Anorexia

Session Chair: Eileen White

Tobias Janowitz Cold Spring Harbor Laboratory, New York, USA

'Interorgan Communication in Cancer Cachexia'

Q&A 15:15-15-25

Hannah Garner McGill University, Montreal, Canada

Proffered Paper 2: 'Understanding how breast tumours hijack myelopoiesis to promote immunosuppression and disease progression'

Q&A 15:35-15:40

POSTER SPOTLIGHTS

3 top-scoring abstracts each presented as a 5 minute talk with 5 minutes Q&A

Danna Breen Pfizer, Cambridge, USA

'Revitalizing Hope: Ponsegromab's (anti-GDF-15) Potential for Breakthrough Targeted Treatment for Cancer Cachexia'

Q&A 16:30-16:40

FLASH TALKS - Session 2

4 abstracts presented as 3-minute flash talks

END OF DAY 1

Listed times are in Central European Time (CET)

WELCOME TO DAY TWO

Session 3: The Metastatic Niche

Session Chair: Tobias Janowitz

Thales Papagiannakopoulos NYU Langone Health, New York, USA

'A dietary switch promotes cancer-associated cachexia in lung cancer'

Q&A 14:25-14:35

FLASH TALKS - Session 3

5 abstracts presented as 3-minute flash talks

Manuel Valiente CNIO, Madrid, Spain

'The brain metastatic niche as a source of systemic vulnerabilities and opportunities'

Q&A 15:15-15:25

Anabel Eckerling Tel Aviv University, Tel Aviv, Israel

Proffered Paper 3: 'Sympathetic regulation of tumor secretome and anti-tumor immunity: Perioperative blockade of β-adrenergic and prostaglandin signaling limits metastatic progression'

Q&A 15:35 - 15:40

REFRESHMENT BREAK

Session 4: Cancer Modulating Immune Response

Session Chair: Eileen White

Ye'ela Scharff Tel Aviv University, Tel Aviv, Israel

Proffered Paper 4: 'Complement signaling is a hallmark of inflammatory fibroblasts in chronic diseases and cancer'

Q&A 16:05-16:10

Adrian Hayday Crick Institute, London, UK

'Bringing cancer immunotherapy to more cancers and to many more people'

Q&A 16:30 - 16:40

KEYNOTE LECTURE

William Kaelin Dana-Farber Cancer Institute, Boston, USA

'Roles of HIF2 and PTHLH in Kidney Cancer-Associated Cachexia: Treatment with a First-In-Class Agent'

Q&A 17:00-17:15

DISCUSSION SESSION

Eileen White (Rutgers Cancer Institute of New Jersey, New Jersey, USA); Karen Vousden (Crick Institute, London, UK); Marcus Goncalves (Weill Cornell Medicine, New York, USA); Tobias Janowitz (Cold Spring Harbor Laboratory, New York, USA)

SUMMARY AND CLOSE