Listed times are in Central European Time (CET)

WELCOME TO DAY ONE

Chair: Maria Caffarel

Raymond Schiffelers UMC Utrecht, Netherlands

'Targeted lipid nanoparticles delivering DNA for in vivo CAR T cell engineering'

Q&A 12:25-12:35

Pablo Menendez Josep Carreras Leukaemia Research Institute, Spain

'Armoured-CAR T cell-redirecting immunotherapy for metastatic and refractory Ewing Sarcoma'

Q&A 12:55-13:05

Chiara Caprioli KU Leuven, Belgium

Proffered Paper 1: 'Unraveling Response to Dendritic Cell Vaccination in Glioblastoma by Spatial Transcriptomics Profiling'

Q&A 13:15-13:20

Myrofora Panagi University of Cyprus, Cyprus

Proffered Paper 2: ‘Engineering the tumor microenvironment with programmable bacteria to enhance immunotherapy’

Q&A 13:30-13:35

INDUSTRY SPOTLIGHT - Lightcast

Scott Brouilette Lightcast

'Envisia: single-cell phenotypic profiling'

REFRESHMENT BREAK

Chair: Federica Sallusto

FLASH TALKS 1

Marleen Kok NKI, Netherlands

'Tumor dynamics during immunotherapy response in breast cancer'

Q&A 14:30-14:40

Luna Ridan Cordeiro Minute Hospital la Paz Institute for Health Research, Spain

Proffered Paper 3: ‘MV130 as a new innate memory-based immunotherapy against cancer’

Q&A 14:50-14:55

REFRESHMENT BREAK

Chair: Toni Celià-Terrassa

FLASH TALKS 2

Pietro Paolo Vitiello IFOM, Italy

Proffered Paper 4: 'The combination of cisplatin and temozolomide triggers immune surveillance through antigen-dependent and independent mechanisms'

Q&A 15:30-15:35

Adriaan de Groot Netherlands Cancer Institute, Netherlands

Proffered Paper 5: 'CD28 glyco-editing augments CD8 T cell:tumor cell interaction and killing’

Q&A 15:45-15:50

CLOSING KEYNOTE

Nathan West Genentech, USA

'Emerging cytokine-based strategies for cancer immunotherapy'

Q&A 16:20-16:35

SUMMARY AND CLOSE

Listed times are in Central European Time (CET)

WELCOME TO DAY TWO

Chair: Arianna Calcinotto

Joaquin Arribas Hospital del Mar Research Institute, Spain

'Turning HER2-Amplified Tumors into CAR-T Responders'

Q&A 12:25-12:35

EMBO Keynote Lecture

Eric Vivier Centre d’Immunologie de Marseille-Luminy, France

'Harnessing NK cells in cancer therapies'

Q&A 12:55-13:05

Marco Piva CIC BIoGUNE, Spain

Proffered Paper 6: 'A novel androgen-responsive metastatic prostate cancer model for rational combination immunotherapy'

Q&A 13:15-13:20

Margo De Velder Ghent University, Belgium

Proffered Paper 7: ‘mRNA lipid nanoparticles alter myeloid cell dynamics in the 4T1 tumor microenvironment’

Q&A 13:30-13:35

REFRESHMENT BREAK

Chair: Toni Celià-Terrassa

FLASH TALKS 3

Victor Peperzak University Medical Center Utrecht, Netherlands

Proffered Paper 8: ‘Enhancing CAR T cell cytotoxicity through targeted delivery of pro-apoptotic cargo’

Q&A 14:15-14:20

Alena Gros VHIO, Spain

'Towards personalized antitumor T-cell therapies from peripheral blood'

Q&A 14:40-14:50

REFRESHMENT BREAK

FLASH TALKS 4

Arianna Calcinotto Institute of Oncology Research, Switzerland

'Neutrophils in cancer: heterogeneous and multifaceted'

Q&A 15:35-15:45

Nicolae Ciobu Zubenco Columbia University, USA

Proffered Paper 9: 'Lipid desaturation as a metabolic checkpoint for T cell immunity suppression in liver cancer'

Q&A 15:55-16:00

DISCUSSION SESSION

Maria Caffarel, Nathan West, Joaquin Arribas

"How to translate the next generation immunotherapies to the clinic?"

CONFERENCE SUMMARY AND CLOSE