EACR-Mark Foundation Joint Conference: The Rise of Early-Onset Cancers - Biology, Causes, and Detection

Bergamo, Italy : 11 - 13 November 2025

Scientific Programme

Tuesday 11th November 2025

Listed times are in Central European Time (CET)

11:30

REGISTRATION (light refreshments will be served at 12:00)

13:00

CONFERENCE WELCOME

SESSION 1: Global landscape of early-onset cancers (1)

Chair: Alberto Bardelli

13:10

Keynote Speaker: Yin Cao Washington University in St. Louis, US

'Accelerating cancer risk factor discovery for younger and future generations'

13:35

Q&A 13:35-13:50

13:50

Ahmedin Jemal American Cancer Society, US

'The changing landscape of early-onset cancers'

14:10

Q&A 14:10-14:20

14:20

Proffered Paper 1

14:30

Q&A 14:30-14:35

14:35

EXHIBITOR INTRODUCTIONS

14:45

COFFEE BREAK, EXHIBITION & SOLO TRAVELLER MEET-UP

15:15

Giulia Martina Cavestro UniSR, Italy

'Diet and lifestyle as associated factors in early-onset colorectal cancer: Preliminary data from the DEMETRA study'

15:35

Q&A 15:35-15:45

15:45

Andrew Biankin University of Glasgow, UK

'Moving away from a one size fits all for young people with cancer'

16:05

Q&A 16:05-16:15

16:15

POSTER SPOTLIGHTS

16:25

INDUSTRY SYMPOSIUM

16:45

Q&A 16:45-16:55

16:55

NETWORKING QUIZ

Our fun, informal quiz offers conference participants the chance to make new connections on the first evening of the meeting

17:25

WELCOME RECEPTION

18:15

POSTER DISCUSSION SESSION 1

Led by members of the Scientific Programme Committee

Wednesday 12th November 2025

Listed times are in Central European Time (CET)

08:15

EARLY POSTER VIEWING

08:45

INDUSTRY SPOTLIGHT - CeGaT

Dr Dmitri Ossipov CeGaT

'21st Century genetic oncodiagnostics'

SESSION 2: Global landscape of early-onset cancers (2)

Chair: Shuji Ogino

09:00

Ulrike Peters Fred Hutchinson Cancer Center, US

'Early onset colorectal cancer: Integrating epidemiological trends with molecular mechanisms'

09:20

Q&A 09:20-09:30

09:30

Proffered Paper 2

09:40

Q&A 09:40-09:45

09:45

Jelle Wesseling Netherlands Cancer Institute, Netherlands

'Ductal Carcinoma In Situ: When cancer is not really cancer'

10:05

Q&A 10:05-10:15

10:15

Mihaela van der Schaar University of Cambridge, UK

10:35

Q&A 10:35-10:45

10:45

COFFEE BREAK & EXHIBITION

11:15

José Perea Biomedical Research of Salamanca, Spain

'Immunometabolic dimension of early-onset colorectal cancer. Paradigm for the other early-onset cancers?'

11:35

Q&A 11:35-11:45

11:45

Proffered Paper 3

11:55

Q&A 1:55-12:00

12:00

POSTER SPOTLIGHTS

12:10

INDUSTRY SYMPOSIUM - SARTORIUS

Gennaro De Vita Sartorius

'Innovative Bioanalytical Tools for Enhanced Live-Cell Imaging'

12:30

Q&A 12:30-12:40

12:40

LUNCH

13:40

POSTER DISCUSSION SESSION 2

Led by members of the Scientific Programme Committee

SESSION 3: Clinical, molecular and biological features

Chair: Salvatore Siena

15:10

Keynote Speaker: Shuji Ogino Harvard University, US

'Assessing long-term risk factor exposures is a critical gap in early-onset cancer research: how can we overcome it using tumor biomarker analyses?'

15:35

Q&A 15:35-15:50

15:50

Proffered Paper 4

16:00

Q&A 16:00-16:05

16:05

Proffered Paper 5

16:15

Q&A 16:15-16:20

16:20

Irit Ben-Aharon Rambam Health Care Campus, Israel

'The evolving enigma- early onset colorectal cancer'

16:40

Q&A 16:40-16:50

16:50

COFFEE BREAK & EXHIBITION

17:20

Nicola Segata University of Trento, Italy

'The microbiome in early-onset colorectal cancer'

17:40

Q&A 17:40-17:50

17:50

The EMBO Keynote Lecture

Alberto Bardelli IFOM, Italy

'The exposome and early onset colorectal cancers'

18:10

Q&A 18:10-18:20

19:30

CONFERENCE DINNER (optional ticketed event)

Thursday 13th November 2025

Listed times are in Central European Time (CET)

08:15

EARLY POSTER VIEWING

08:45

INDUSTRY SPOTLIGHT

SESSION 4: Experimental models

Chair: Yin Cao

09:00

Cheryl Walker Baylor College of Medicine, US

'Epigenomic reprogramming by early life environmental exposures alter cancer risk in adulthood'

09:20

Q&A 09:20-09:30

09:30

Gianluca Mauri Ospedale Niguarda, Italy

'From biological understanding to personalized clinical management of early-onset colorectal cancer'

09:50

Q&A 09:50-:10:00

10:00

Proffered Paper 6

10:10

Q&A 10:10-10:15

10:15

COFFEE BREAK & EXHIBITION

10:45

Selma Masri UC Irvine, US

'Circadian Clock Misalignment in Colorectal Cancer: Links with Early-Onset Disease'

11:05

Q&A 11:05-11:15

11:15

KEYNOTE LECTURE

Sir Mike Stratton Wellcome Sanger Institute, UK

'Mutagenic exposures to normal colorectal epithelium and their potential role in early-onset colorectal cancer'

11:40

Q&A 11:40-11:55

11:55

SUMMARY & AWARDS

12:15

DEPART

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