Listed times are in Central European Summer Time (CEST)

REGISTRATION & WELCOME LUNCH

CONFERENCE WELCOME

Session 1

Chair: Joan Seoane

OPENING KEYNOTE LECTURE

Alberto Mantovani Humanitas University, Italy

"Innate immunity, inflammation and cancer from bench to bedside"

Q&A: 13:40-13:55

Jennifer Guerriero Brigham and Women’s Hospital / Harvard Medical School, USA

“Targeting novel populations of macrophages for anti-cancer therapy”

Q&A: 14:15 - 14:25

Krijn Dijkstra Antoni van Leeuwenhoek - Netherlands Cancer Institute, Netherlands

Proffered Paper 1: "Patient-derived co-cultures of TRACERx lung cancer organoids and autologous T-cells reveal heterogeneity in immune evasion between cancer subclones"

Q&A: 14:35 - 14:40

EXHIBITOR INTRODUCTIONS

60-second intro pitches by each company

COFFEE BREAK & EXHIBITION

Session 2

Chair: Ignacio Melero

Joan Seoane Vall d'Hebron Institute of Oncology (VHIO), Spain

"Impact of the tumor microenvironment on immunotherapy"

Q&A: 15:40 - 15:50

Sonia Guedan Hospital Clínic de Barcelona, Spain

"CAR-T cells for the treatment of solid tumors"

Q&A: 16:10 - 16:20

Poster Spotlights

3 top abstracts presented as 3-minute flash talks

Alena Gros Vall d'Hebron Institute of Oncology (VHIO), Spain

"Towards tailored antitumor T-cell therapies"

Q&A: 16:50 - 17:00

Gabriel Rabinovich The Institute of Biology and Experimental Medicine/CONICET, Argentina

"The emerging role of glyco-checkpoints in cancer: the 'sweet' side of immunotherapy"

Q&A: 17:20 - 17:30

Welcome Reception

Drinks reception with buffet.

POSTER DISCUSSION SESSION 1

Listed times are in Central European Summer Time (CEST)

Poster viewing

Posters may be freely viewed. Tea/coffee/biscuits will be served..

Session 3

Chair: Lillian Siu

INDUSTRY SPOTLIGHT - Agilent Technologies

Miriam Contreras Mostazo Agilent

"How to assess T cell metabolic profile and further develop effective T cell therapies using Seahorse Analyzer"

Ignacio Melero Clínica Universidad de Navarra, Spain

"Tumor IL-8, NETs and the wrong type of tumor inflammation"

Q&A: 09:20 - 09:30

Jörg Wischhusen University Hospital Würzburg, Germany

Proffered Paper 2: "Tumor-derived GDF-15 prevents therapy success of checkpoint inhibitors by blocking T-lymphocyte recruitment"

Q&A: 09:40 - 09:45

Keren Yizhak Technion - Israel Institute of Technology, Israel

"Estimating tumor mutational burden from 'tumor-only' RNA-sequencing data"”

Q&A: 10:05 - 10:15

Mustafa Diken Germany

“The evolution of mRNA-vaccines against cancer”

Q&A: 10:35 - 10:45

COFFEE BREAK & EXHIBITION

THE EMBO KEYNOTE LECTURE

Yardena Samuels Weizmann Institute of Science, Israel

"Revisiting the Neoantigen Approach for Cancer Immunotherapy"

Q&A: 11:35 - 11:45

Macarena Román VHIO, Spain

Proffered Paper 3 : "p95HER2 CAR Ts secreting HER2 BITEs are a safe and effective immunotherapeutic strategy against HER2-positive tumors."

Q&A: 11:55 - 12:00

Poster Spotlights

3 top abstracts presented as 3-minute flash talks

INDUSTRY SYMPOSIUM - Bio-Rad Laboratories

Andrés Ramírez, PhD Flow Cytometry Regional Specialist, Bio-Rad

“Overcoming Bottlenecks in Research & Discovery with High-Throughput Flow Cytometry"

LUNCH & EXHIBITION

POSTER DISCUSSION SESSION 2

Session 4

Chair: Yardena Samuels

Industry Spotlight - LynxCare

Dr. Annelies Verbiest, PhD Department of Oncology, Antwerp University Hospital, Belgium

“Defense through Insights: Using AI to Unlock Real-World Evidence in Immunotherapy”

KEYNOTE LECTURE

Tyler Jacks MIT - Massachusetts Institute of Technology, USA

"Genetic engineering meets tumor immunology: Lessons from mouse models of cancer."

Q&A: 15:35 - 15:50

Lillian Siu University of Toronto, Canada

"Circulating DNA Applications in the Immuno-Oncology Era"

Q&A: 16:10 - 16:20

Marni Nishimoto Johns Hopkins, USA

Proffered Paper 4: "Transcriptional Programs of Tumor Specific CD4+ T Cells in NSCLC"

Q&A: 16:30 - 16:35

Giuseppina Arbore Ospedale San Raffaele, Italy

Proffered Paper 5: "Immune determinants of response to neoadjuvant chemotherapy in esophageal adenocarcinoma."

Q&A: 16:45 - 16:50

COFFEE BREAK & EXHIBITION

Chair: Joan Seoane

Pablo Umaña Roche, Switzerland

"Enhancing endogeneous and synthetic immunity with engineered antibody-fusion proteins for cancer immunotherapy"

Q&A: 17:40 - 17:50

Sergio Quezada Cancer Research UK, UK

"Regulatory T cells as Determinants of Adaptive and Innate Immune Function in Brain Tumours"

Q&A: 18:10 - 18:20

Meet the Scientific Programme Committee

Joan Seoane, Lillian Siu, Alena Gros, Ignacio Melero & Yardena Samuels

Our esteemed Scientific Programme Committee will come together to each provide insight into their personal and professional experiences of their routes into scientific leadership.

Conference Dinner

The dinner is being held at the 5* rated Hotel Casa Fuster, located just a short walk away from La Pedrera. Optional ticketed event. The dinner will end at 22:00 CEST.

Listed times are in Central European Summer Time (CEST)

Poster viewing

Posters may be freely viewed. Tea/coffee/biscuits will be served.

Session 5

Chair: Alena Gros

Andrea Ablasser EPFL, Switzerland

"Sensing DNA as a danger signal through the cGAS-STING pathway"

Q&A: 09:20 - 09:30

Marisol Soengas CNIO (Spanish National Cancer Research Centre), Spain

“Dissecting and targeting immune suppressive signals in the melanoma microenvironment”

Q&A: 09:50 - 10:00

Eudald Felip Institut Catala Oncologia, Spain

Proffered Paper 6: "Enhanced tumor immunity determines CDK4/6 inhibitor efficacy in advanced breast cancer (BC)."

Q&A: 10:10 - 10:15

COFFEE BREAK & EXHIBITION

Susan Galbraith (Pre-recorded Presentation) Astrazeneca, UK

‘Exploring the next wave of immuno-oncology therapies’

CLOSING KEYNOTE LECTURE

Josep Tabernero Vall d'Hebron Institute of Oncology (VHIO), Spain

Q&A: 11:45 - 12:00

SUMMARY & AWARDS

Depart