Listed times are in Central European Time (CET)

WELCOME TO DAY ONE

Opening words: James Hadfield

Session 1: Horizons for Liquid Biopsy

Session Chair: James Hadfield

KEYNOTE LECTURE

Yuval Dor Hebrew University of Jerusalem, Jerusalem, Israel

'Epigenetic liquid biopsy'

Q&A 13:25-13:40

Viktor Adalsteinsson Gerstner Centre for Cancer Diagnostics, Broad Institute, Cambridge, USA

'Modulating cfDNA biology to enhance liquid biopsies'

Q&A 14:00-14:15

Davina Gale AstraZeneca, Cambridge, UK

'Pathway to cure: application of ctDNA in clinical trials'

Q&A 14:35-14:50

REFRESHMENT BREAK

Session 2: Liquid biopsies for breast and lung cancers

Session Chairs: Davina Gale and James Hadfield

Heather Parsons Dana-Farber Cancer Institute, Boston, USA

'How low should we go? ctDNA to detect MRD in breast cancer'

Q&A 15:25-15:40

Andreas Risch MGZ Munich, Munich, Germany

Proffered Paper 1: 'Liquid biopsy analysis of advanced breast cancer patients – A real-life perspective of actionable variants'

Q&A 15:50-15:55

Albert Grinshpun Shaare Zedek Medical Center, Jerusalem, Israel

Proffered Paper 2: 'Utilization of cfDNA in Detecting Drug-Induced Lung Toxicity'

Q&A 16:05 - 16:10

Max Diehn Stanford University School of Medicine, Stanford, USA

'Liquid biopsies for detection and characterization of lung cancers'

Q&A 16:30-16:45

SPOTLIGHT PRESENTATIONS

3 five minute Spotlight talks, from high-scoring abstracts submitted to the meeting.

FLASH TALKS - Session 1

A selection of short 3-minute flash talks from selected abstracts submitted to the meeting.

END OF DAY 1

Listed times are in Central European Time (CET)

WELCOME TO DAY TWO

Session 3: Liquid biopsy in colorectal and bladder cancers

Session Chair: Evi Lianidou

Naureen Starling The Royal Marsden NHS Foundation Trust, London, UK

'Circulating nucleic acids (cfDNA/ctDNA): in use, in view and on the horizon’ a GI perspective but with broader applicability'

Q&A 14:25-14:40

Silvia Marsoni IFOM, Milan, Italy

'Leveraging liquid biopsy to deconvolute colon cancer biology'

Q&A 15:00-15:15

Lars Dyrskjøt Aarhus University. Aarhus, Denmark

'Towards ctDNA-guided treatment of muscle-invasive bladder cancer'

Q&A 15:35-15:50

REFRESHMENT BREAK

Session 4: Next generation liquid biopsy researchers

Session Chair: Caroline Dive

Daniel Hagey Karolinska Institutet, Stockholm, Sweden

Proffered Paper 3: 'Dynamic size and association profiles of tumour-derived DNA during pancreatic cancer progression'

Q&A 16:15-16:20

Lucy Faulkner University of Cambridge, Cambridge, UK

Proffered Paper 4: 'Assessing response to androgen deprivation and surgery using methylation sequencing of ctDNA from plasma and urine in localised prostate cancer'

Q&A 16:30-16:35

FLASH TALKS - Session 2

A selection of short 3-minute flash talks from selected abstracts submitted to the meeting.

KEYNOTE LECTURE

Victor Velculescu Johns Hopkins University School of Medicine, Baltimore, USA

'Early Detection of Cancer using cell-free DNA Fragmentomes'

Q&A 17:10-17:25

DISCUSSION SESSION

Clinical implementation and new technologies

Silvia Marsoni (Chair), IFOM, Milan, Italy; Caroline Dive, CRUK Manchester, UK; James Hadfield, AstraZeneca, Cambridge, UK; Davina Gale, AstraZeneca, Cambridge, UK

SUMMARY AND CLOSE