Listed times are in Central European Summer Time (CEST)

REGISTRATION & WELCOME LUNCH

CONFERENCE WELCOME

SESSION 1: Metabolic signalling in cancer

Chair: Arkaitz Carracedo

OPENING KEYNOTE LECTURE

Eileen White Rutgers Cancer Institute of New Jersey, USA

'Metabolic alterations driving cancer cachexia'

Q&A: 13:40-13:55

Naama Kanarek Boston Children's Hospital / Harvard Medical School, USA

'Metabolic Vulnerabilities of Leukemia that Spreads to the Central Nervous System'

Q&A: 14:15 - 14:25

Naiara Santana Codina Aarhus University, Denmark

Proffered Paper 1: "Defining and Targeting Mechanisms of Acquired Resistance to Nucleotide Synthesis Inhibition in Pancreatic Cancer"

Q&A: 14:35 - 14:40

EXHIBITOR INTRODUCTIONS

COFFEE BREAK, EXHIBITION & SOLO TRAVELLER MEET-UP

Nicla Lorito University of Florence, Italy

Proffered Paper 2: "FADS1/2-mediated lipid metabolic reprogramming drives ferroptosis sensitivity in metastatic triple negative breast cancer"

Q&A: 15:30 - 15:35

Arkaitz Carracedo CIC Biogune, Spain

'Post-transcriptional control of metabolism (and viceversa) in cancer and beyond'

Q&A: 15:55 - 16:05

Mónica Cremades Rodelgo CECAD, Germany

Proffered Paper 3: "The link between mitochondrial ultrastructure and innate immune response upon Fumarate Hydratase loss"

Q&A: 16:15-16:20

Poster Spotlights

3 top abstracts presented as 3-minute flash talks

INDUSTRY SYMPOSIUM - GemPharmatech

Xiangli Bian Project Manager, GemPharmatech Co., Ltd

'KOAP: Genetically Modified Mouse Models and Applications'

MEET THE EXPERTS

Naama Kanarek (Boston Children's Hospital / Harvard Medical School , USA) & Marcus Goncalves (Weill Cornell Medicine, USA)

Dr. Kanarek & Assist. Prof Goncalves will host an informal session where they will each share their own personal and professional experiences of their paths to scientific leadership.

WELCOME RECEPTION

Drinks reception with buffet.

POSTER DISCUSSION SESSION 1

Listed times are in Central European Summer Time (CEST)

EARLY POSTER VIEWING

Posters may be freely viewed

INDUSTRY SPOTLIGHT - Agilent Technologies

Alfredo Caro-Maldonado Seahorse-RTCA xCelligence Field Application Scientist, Agilent Technologies

'Advanced Tools for Cell Therapy Research and Development'

SESSION 2: Metabolic cross talk with the tumour microenvironment

Chair: Matt Vander Heiden

Elisabeth Letellier University of Luxembourg, Luxembourg

'De-coding microbial metabolism in cancer'

Q&A: 09:20 - 09:30

Petra Hyrossova Czech Academy of Sciences, Czech Republic

Proffered Paper 4: "Endothelial pyrimidine synthesis deficiency promotes tumor growth"

Q&A: 09:40 - 09:45

THE EMBO KEYNOTE LECTURE

Karen Vousden The Francis Crick Institute, UK

'Metabolic crosstalk between the tumour and the host"'

Q&A: 10:05 - 10:15

Payam Gammage Cancer Research UK Scotland Institute, UK

'Redox imbalance and anti-tumour immunity'

Q&A: 10:35 - 10:45

COFFEE BREAK & EXHIBITION

Wilhelm Palm DKFZ, Germany

'Metabolic stress adaptations in cancer'

Q&A: 11:35 - 11:45

Peio Azcoaga BIODONOSTIA, Spain

Proffered Paper 5: "Oncostatin M cytokine signalling orchestrates immune remodelling and metabolism within the breast tumour microenvironment"

Q&A: 11:55 - 12:00

Poster Spotlights

7 top abstracts presented as 3-minute flash talks

LUNCH & EXHIBITION

POSTER DISCUSSION SESSION 2

Session 3: Metabolic processes that influence cancer progression and treatment

Chair: Alexia-Ileana Zaromytidou

Martin Bergo Karolinska Institutet, Sweden

'Antioxidants stimulate blood flow in tumours'

Q&A: 15:20 - 15:30

Paula Duch Cancer Research UK Scotland Institute, UK

Proffered Paper 6: "Harnessing epigenetics to reprogram cancer-associated fibroblasts in metastatic breast cancer"

Q&A: 15:40 - 15:45

Hamza Furkan Alkan UT Southwestern Medical Center, USA

Proffered Paper 7: "Metabolic Regulation of Melanoma Immunogenicity and Metastasis"

Q&A: 15:55 - 16:00

COFFEE BREAK & EXHIBITION

KJ Patel Weatherall Institute of Molecular Medicine (University of Oxford), UK

'Endogenous formaldehyde – a toxic metabolic source and modulator of 1 Carbon metabolism'

Q&A: 16:50 - 17:00

Patricia Altea Manzano Cabimer, Spain

"Emerging roles of fatty acid metabolism in metastasis"

Q&A: 17:20 - 17:30

MEET THE EDITORS

Join us in this session led by Dr Alexia-Ileana Zaromytidou, Chief Editor at Nature Cancer, to hear advice about the world of publishing in a relaxed and informal setting. Scheduled to end at 18:15.

Conference Dinner - SOLD OUT!!

The conference dinner will take place at Kafe Antzokia Restaurant. After dinner, we will enjoy music and dancing with a live DJ. This event has now sold out and there are no further tickets available.

Listed times are in Central European Summer Time (CEST)

EARLY POSTER VIEWING

Posters may be freely viewed.

INDUSTRY SPOTLIGHT - CancerTools.org

Dr Seema Sharma CancerTools.org

'A transformative approach to support cancer researchers'

Session 4: Systemic metabolic changes and cancer progression

Chair: Karen Vousden

Marcus Goncalves Weill Cornell Medicine, USA

'Lung cancer induced metabolic derangements driving cachexia'

Q&A: 09:20 - 09:30

Alejo Efeyan CNIO, Spain

'Nutrient signaling in cancer cells and in the stroma – the Goldilocks effect'

Q&A: 09:50 - 10:00

Raphael Morscher University Children's Hospital Zürich, Switzerland

Proffered Paper 8: "Reprogramming neuroblastoma by diet-enhanced polyamine depletion"

Q&A: 10:10 - 10:15

COFFEE BREAK & EXHIBITION

Matthew Vander Heiden Koch Institute for Integrative Cancer Research, USA

'The influence of metabolism on cancer progression'

Q&A: 11:05 - 11:15

CLOSING KEYNOTE LECTURE

Ayelet Erez Weizmann Institute of Science, Israel

'Exploring the tumor Macro-environment to improve cancer diagnosis and therapy'

Q&A: 11:45 - 12:00

SUMMARY & AWARDS

Depart